local intelligence

can it run

Can the AMD Instinct MI355X 288GB run gpt-oss 20B MoE?

FULL

14.2 GB needed of 288 GB usable — headroom for context

288GB · CDNA4 · model file 14GB · 20B MoE

~1100–1700 tok/s (active-expert estimate)

computed roofline: 8000 GB/s × 0.28–0.45 efficiency window / 2.1GB (Q4_K_M) — bands, never points.

MoE: file is 14GB (that decides fit) but only ~3B of experts activate per token (~2.1GB streamed) — band below is the active-expert estimate, optimistic; community MoE rows run several× the naive bandwidth math

Run gpt-oss 20B MoE on instead

Tesla M40 (24GB, used) — cheapest catalog machine that runs gpt-oss 20B MoE fully ($50)

NVIDIA DGX Station (GB300) — upgrade path machine

every model the AMD Instinct MI355X 288GB can run — full list

explore the full catalog90 machines indexed · live prices · what each one can run
2026-09-24 · ← all models on the AMD Instinct MI355X 288GB · fit = weights + 4k KV vs usable memory