can it run
Comfortably. 384GB of memory against a 178GB working set leaves headroom for context, the OS, and anything else you're running.
weights 142GB + KV cache 0.73GB at 4k context vs ~96GB usable → no. 142.7 GB vs 96 GB usable — does not fit
computed roofline: 1792 GB/s × 0.46–0.76 efficiency window / 13.3GB (Q4_K_M) — bands, never points.
MoE: file is 142GB (that decides fit) but only ~22B of experts activate per token (~13.3GB streamed) — band below is the active-expert estimate, optimistic; community MoE rows run several× the naive bandwidth math
| model file | 142GB (GGUF Q4_K_M) |
| minimum memory | 178GB working set |
| this machine | 384GB VRAM (4× 96GB) |
| params | 235B-A22B MoE |
| license | apache-2.0 |
| price | $91000 |
easy run: ollama pull qwen3:235b-a22b
runs with: ollama · llama.cpp · koboldcpp · lm studio
→ ASUS ExpertCenter Pro ET900N G3 (GB300) — this model on the biggest machine